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The Science of Ageing: Energy Decline vs Oxidative Stress Ageing is an interconnected process, but two of the most significant are declining cellular energy and increasing oxidative stress

Some researchers have shown that metformin activates AMPK and triggers the downstream GSH system to slow DOX-mediated oxidative impairment in the myocardium [225, 226]

Human-mouse comparison identifies shared AD pathways To investigate the relevance of the mouse models, we compared the DEPs in 5xFAD and NLGF with human metadata 36,37,52,60

Cell 184 (16), 42684283.e20

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