They work by mimicking the effects of GLP-1, a hormone the gut produces that regulates blood sugar levels
For Mojsov this proved her hypothesis that GLP-1 (1-37) is a prohormone that is enzymatically cleaved to release the biologically active GLP-1 (7-37) (Nair)
Common Side Effects Facial flushing or warmth Nausea, stomach discomfort Chest tightness or pressure (usually dose/rate dependent) Headache Fatigue after administration Injection site discomfort, redness, or swelling Mild dizziness Seek Medical Attention For Severe chest pain or difficulty breathing Signs of allergic reaction: hives, facial swelling, throat tightness Fainting or severe dizziness Use in Pregnancy and Breastfeeding The safety of NAD+ therapy during pregnancy and breastfeeding has not been established
Several compounded programmes work the same way, with reported ladders reaching $299 or $499 at maintenance doses
Stareini M, Sebei B, Patrlj L, et al