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Silencing TFRC, the gene encoding TFR 1, can inhibit erastin-induced ferroptosis 25 , while heme oxygenase-1 (HO-1) can accelerate erastin-induced ferroptosis by supplementing iron 26

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Mol Metab 20 , 5162 (2019)

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Hydroxocobalamin is preferred because it binds more tightly to serum proteins, creating a depot effect that allows slower release and longer duration of action

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