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A prominent mechanism in functional GI disorders such as IBS is the modulation of the gut-brain axis
72 Interestingly, a meta-analysis reported that SEMA significantly reduces liver stiffness (mean difference = 3.08 kPa
Shrinks fat cells in mice In diet-induced obese mice, 11 days of 5-Amino-1MQ (subcutaneous, around 34 mg/kg/day) reduced body weight, total fat mass, and plasma cholesterol with no drop in food intake or lean mass
DN and associated complications Diabetic foot disease is significantly exacerbated in patients with DPN due to reduced sensation and impaired wound healing, elevating the risk of foot ulcers and infections and potentially leading to lower-limb amputations
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