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Regulation of the Pentose Phosphate Pathway The major regulator of the PPP is the cellular response to oxidative stress

The commercial effect: by the time biosimilar competition launched in January 2023, a substantial fraction of Humira patients had already been transitioned to the citrate-free, high-concentration formulation

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Accordingly, metabolic labeling showed a wild-type-like [ 3 H]palmitate incorporation for MGNC-Nt 7 and only the residual signal for MGNTC-Nt 7 (Supplementary Fig