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Lilly has demonstrated their ability to bring complex peptide therapies through the regulatory process, and their phase 3 TRIUMPH trial program for retatrutide includes multiple studies across different patient populations
What are the downsides of copper peptides
Prognostic factors in the treatment of alopecia areata with diphenylcyclopropenone
Many clinical observations suggest use 2-3 times per week rather than daily, with cycling periods to help maintain response over time
However, big pharma will still have the ability to charge premium prices for innovator molecules, especially those with higher efficacy (eg retatrutide) and those aimed at niche patient populations rather than the mass market (eg survodutide, which is targeting MASH endpoints in clinical trials)
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