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The results showed significant positive regulation of innate and peripheral inflammatory responses and cytokine expressions, such as the nuclear factor (NF)-kB pathway, TNF signaling pathway, Toll-like receptor signaling pathway, Janus kinase (JAK)/STAT pathway, NLRP3, IL-1, IL-6, TNF, and IL-17, which indicated that the inflammatory response following TBI played crucial roles in the process of secondary brain injury

Stability testing of new drug substances and products Q1A(R2)

Real-world HCRU and medical costs can be important factors in deciding which ADM to initiate, and further research is warranted on these outcomes for patients with T2D

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doi:10.3389/fnins.2022.833202