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In addition, carnitine also depletes mitochondrial and ER Ca 2+ storage by activating phospholipase C, further increasing the intracellular Ca 2+ concentration
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We did not observe any significant group differences in brain GSH or circulating concentrations of peripheral blood markers
Therefore, hyperhomocysteinemia-induced depletion of TH may not involve in the development but only in the progression of PD through the degeneration of dopaminergic neurons with secondary deficiency of TH in PD (Kawahata and Fukunaga 2020
Possible bowel obstruction
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