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1 Psychosocial and metabolic stress , the physiological burden of adapting to a new medication and a changing body composition, can itself be a shedding trigger
McLean BA, Wong CK, Kabir MG, Drucker DJ (2022) Glucagon-like Peptide-1 receptor Tie2+ cells are essential for the cardioprotective actions of liraglutide in mice with experimental myocardial infarction
Duration of Benefit The health benefits of GLP-1R agonists are most pronounced within the first year of treatment, with significant improvements in glycated hemoglobin (HbA1c), body mass index (BMI), and cardiovascular outcomes
A careful escalation schedule gives the body time to adapt while allowing the provider to adjust the pace based on how the patient is responding
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