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On the contrary, GLP-1 suppresses glucagon secretion in both healthy individuals and those with T2DM under normoglycemia and hyperglycemia (58) but not during hypoglycemia (131), thereby reducing the potential for developing severe hyperglycemia or hypoglycemia
Since weight loss is typically associated with muscle loss, the concern with GLP-1 drugs is whether these medications induce excessive muscle loss than expected for the achieved decline in weight
The side effects typically resolve on their own
and lifestyle changes such as sleep, stress, and mood support
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