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The activity of the COX enzyme relies on its being in the oxidized form to be specific, tyrosine 385 must be oxidized to a radical
The synthesis of [ 68 Ga]Ga-DO3A-Tuna-2 and [ 68 Ga]Ga-DO3A-Exendin-4 was developed based on, respectively a manual labelling procedure 7 and automated procedure 16 developed earlier
Combined, these effects disrupt normal cyclic hormone patterns, change feedback to the hypothalamus and pituitary, and can result in irregular cycles, low sperm quality, or anovulation
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