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Mutations of OCTN2, an organic cation/carnitine transporter, lead to deficient cellular carnitine uptake in primary carnitine deficiency
A current medicine list, including supplements and over-the-counter products, helps the prescriber assess these risks
These genes are designated CYP4F8, CYP4F11, and CYP4F12
& Shi, G
Thiamine deficiency in causes neurological injury leading to the Wernicke/Korsakoff syndrome ( FIGURE 2 via effects on homocysteine/methionine metabolism as well as DNA methylation
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