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The main restraint is regulatory scrutiny of promotion, especially claims about compounded GLP-1 products and product equivalence
10.1124/pr.111.004846 81 LiQ.YueY.ChenL.XuC.WangY.DuL.et al (2018)
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Serial blood samples were collected for PK analysis at pre-specified intervals up to 672 h after the final dose (pre-dose, 4, 6, 12, 24, 36, 48, 72, 120, 168, 336, and end-of-study at 672 h)
Supply and oral drugs the difficulty of manufacturing GLP-1s could be addressed by a company demonstrating efficacy, and more importantly, safety of an oral non-peptide GLP-1
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