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This visual indicator can help researchers assess compound integrity, though formal verification relies on the batch-specific Certificate of Analysis

10.1021/acs.biochem.7b00942 27 CookeP

Under unfolded protein stress conditions, GRP78 binds to unfolded or misfolded proteins and subsequently activates downstream ER stress sensors, including IRE1, PERK, and ATF6, to trigger a response to unfolded proteins (Yoboue et al., 2017) , (Wei et al., 2012)

Atkinson and Walton, 1967), but needs to be catalyzed by kinases and phosphatases to reach the required reaction velocities and specificity

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