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Am J Clin Nutr 1990;52(5):889-894
This induction often occurs via activation of Nrf2 (Nuclear factor erythroid 2-related factor 2), a key transcription factor in the antioxidant response pathway
This is not a jumpstart
Circulation 131 , 16911702 (2015)
The only FDA-approved treatments (disulfiram, naltrexone, and acamprosate) have been modestly successful in treating AUD (e.g., naltrexone reduces relapse rates by 5%) (for a detailed review and meta-analysis 1,2 ), but still are severely under-prescribed
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