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CagriSema produced unprecedented mean weight loss of 20.4% at 68 weeks on an intent-to-treat basis, significantly exceeding semaglutide alone (14.9%), cagrilintide alone (11.5%), and placebo (3.0%)
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Unlike traditional anti-angiogenic therapies that target VEGF, Sylentis developed SYL1801, an siRNA targeting NOTCH Regulated Ankyrin Repeat Protein (NRARP), to prevent and control nAMD progression
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