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doi: 10.1016/j.mam.2004.06.006 13
Because these medications have a narrow therapeutic indexmeaning the difference between a helpful dose and a risky dose is quite smallany factor that changes how they are absorbed or metabolized is important to track
Compounded versions are prepared by 503A pharmacies under individualized prescription, which allows more flexible dosing, useful when a patient needs a dose between standard pen strengths or has specific clinical needs the branded product cannot accommodate
None of these are approved for human use in France research use only.
