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En personas sin deficiencia de L-Carnitina, la ingesta de 3 g/da divididos en 3 tomas, durante 10 das, demostraron de manera concluyente que produca un aumento de la oxidacin de cidos grasos de cadena larga [2]
We also acknowledge that the study has some limitations
This observed risk profile likely stems from two pharmacological factors: (1) the contraindication of metformin in patients with renal insufficiency, and (2) the potential dehydrating effects associated with GLP-1 receptor agonists
Careful monitoring is needed
PLoS ONE 7(4):e35008
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