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Stability of Protein Pharmaceuticals: An Update

But some patients notice something unexpected during their weight loss journey: New or worsening back pain

Practically, the interchangeability standard requires a switching study demonstrating that patients who alternate between the reference biologic and the biosimilar multiple times do not develop higher rates of anti-drug antibody formation, infusion reactions, or loss of efficacy compared to patients who remain on the reference product throughout the study

Key takeaways Wegovy injection or tablets can sometimes cause unusual skin sensations like tenderness, burning, tingling, or pain to the touch, though these skin side effects are more common at higher doses

Zhu J, Zhong Z, Shi L, Huang L, Lin C, He Y, et al