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[76] [77] In a 72-week, phase IIIb open-label head-to-head trial of adults with obesity without diabetes, tirzepatide at the maximum tolerated dose produced greater mean weight loss than semaglutide and larger reductions in waist circumference, while gastrointestinal adverse events were the most common with both drugs
Tumor-educated T(regs) drive organ-specific metastasis in breast cancer by impairing NK cells in the lymph node niche
Example: 2mg or 500mcg
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Given these inconsistencies, direct interchangeability between the two modalities is not recommended, and standardized imaging protocols or regression-based conversion equations should be applied to ensure measurement comparability in longitudinal studies [16]
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