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As an alternative possibility, the GPx1 deficiency in intestinal macrophages could be due to increased utilization of selenium for selenoprotein production elsewhere as serum GPx activity was increased in patients with active CD
*The oxidative stress marker *-OHdG decreased by 96% in the first 14 days, maintaining an 87% decrease after 28 days
However, when liver cells from old patients were incubated in the blood from the younger group, the older cells started functioning in nearly the same way as the younger liver tissue
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