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DOI: Published online: April 25, 2016 Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea
By phase, the phase I segment is expected to grow significantly during the forecast period
Patient education regarding expected side effects and practical strategies can help minimize discomfort while maintaining therapeutic benefit from diabetes or weight management treatment
Sex was not considered as a biological variable in the primary study design because (i) cyclical hormonal variation in female mice is a known confounder of LPS-induced inflammatory cytokine responses, and (ii) the C57BL/6J LPS doseresponse and time course on which our paradigm was based has been characterized primarily in males in prior literature
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