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It is biologically defined by two main microscopic features in the brain: amyloid-beta plaques and neurofibrillary tangles
DPP-4 is a serine protease that rapidly inactivates endogenous GLP-1 and GIP by cleaving the N-terminal His-Ala dipeptide
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In a healthy person, GLP-1 levels rise after a meal, tell the brain you are full and then go away
Dailey MJ, Moran TH
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