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As a GLP-1 receptor agonist, it mimics a naturally occurring gut hormone that slows down how quickly food leaves your stomach, signals areas of the brain that regulate appetite, and helps your pancreas release insulin more effectively

For these drugs to be worth the high costs, they need to show clear benefits and savings for the wider health care system

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No unexpected safety signals (pancreatitis, thyroid tumor, severe hypoglycemia in the non-diabetic population) were reported above expected background rates in the Lilly summary