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Artificial overexpression of GPx1 showed an increased capacity to rescue breast cancer cells from the cell cycle arrest caused by hyperoxic stress, indicating the involvement of both peroxide-derived free radicals and nonperoxide-derived species during the deleterious process [84]
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We tested two forms of antisense oligonucleotides to knockdown (KD) caspase-3 (C3) in a total liver (hepatocytes and NPCs) or in a hepatocyte-specific manner
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