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Smaller, lighter meals spread throughout the day are usually easier to tolerate
Fortunately, simple awareness prevents most problems before they occur
In rare cases, more serious risks can occur, such as pancreatitis, acute kidney injury, gallbladder issues
Studies in gliomas using transcriptomics and proteomics have revealed that chaperone-mediated autophagy (CMA) and its primary receptor LAMP2A, located on the lysosomal membrane, modulate CSC behavior through mechanisms such as extracellular matrix interactions, mitochondrial metabolism, and immune system pathways [108]
this has contributed to acquiring a better physiological understanding of their metabolism in humans, while also highlighting the challenges and limitations of the current trials
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