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Far more research is needed
Months 12+: Long-Term Results Average weight loss: 14-15% by month 16-17 (28-30 pounds for a 200-pound person) In the STEP-1 trial, participants reached their maximum weight loss around week 60-68 (months 14-16)
People with cardiovascular concerns or high blood pressure need careful screening before using it
Still, many people who start tirzepatide report dry mouth, especially in the first weeks or after dose increases
It also produces more significant weight lossclinical trials show an average of 15% body weight reduction compared to 5-10% with many other medications
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