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The brain doesnt respond to these drugs in a static wayit adapts. The team is also exploring molecular changes in peripheral tissues, such as liver, fat, and muscle, that may underlie the observed shift from fat to carbohydrate use during weight maintenance

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According to the Direct Meds website, their semaglutide protocol starts at 0.25mg per week for the first four weeks, then increases to 0.5mg per week, with physician-directed adjustments as appropriate