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New Phytol 191(2):349359

Do not site for more than 20 minutes at a time

Current evidence supports interpreting patient-reported "taste changes" within a sensory-liking-wanting framework that distinguishes sensory perception from food enjoyment and craving

They have lots of different effects and we are in the early stages of exploring peptide therapeutics

Healthcare providers may avoid prescribing topiramate for individuals with a history of: Suicidal thoughts or behaviors Kidney stones Metabolic acidosis Bone conditions like osteopenia, osteomalacia, or osteoporosis Glaucoma Respiratory issues like asthma or COPD Depression or mood disorders Growth problems Thyroid, liver, or kidney disease Because topiramate can increase the risk of kidney stones, its important to stay well-hydrated while taking the medication