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The post hoc analysis of pooled data from the Semaglutide Treatment Effect in People with Obesity (STEP) 1, 2, 3, and 5 trials indicated that semaglutide treatment at 2.4 mg did not increase the risk of depressive symptoms or suicidal ideation compared to placebo, while demonstrating a statistically significant yet clinically negligible decrease in depressive symptoms [75]
DOI: 10.1183/13993003.00161-2019 [Google Scholar] Garvey WT, Batterham RL, Bhatta M, Buscemi S, Christensen LN, Frias JP, et al
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At this concentration, a 500 mcg dose equals 0.2 mL (20 units on an insulin syringe)
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