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Obesity contributes to the development and progression of Type 2 diabetes, a disease characterized by high blood sugar levels, insulin resistance, and a relative lack of insulin
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By improving capillary blood flow and microvascular tone, this pathway aids in vascular remodeling by preventing vascular constriction and capillary collapse, which are common in retinal diseases like DR and ischemic retinopathy
Both the android-to-gynoid fat ratio and trunk-to-leg fat ratio were significantly reduced in the 8mg group, indicating that retatrutide preferentially targets the most metabolically harmful fat deposits
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