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Total loss of 1015% (semaglutide) or 1522% (tirzepatide) typical by month 12

When starting GLP-1 medications, doctors usually begin with a low dose and increase it slowly over several weeks or months to reduce side effects, especially nausea and stomach upset

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Thymosin-4derived peptides (TB-500) further contribute by regulating macrophage and neutrophil dynamics during tissue repair and infection, supporting controlled recruitment of innate immune cells and facilitating transition toward resolution-phase healing (33,34)