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When it binds to receptors on pancreatic beta cells, it stimulates glucose-dependent insulin secretion, meaning insulin is released only when blood glucose is elevated

GLP-1 receptors are found not only in the pancreas but also in immune cells, indicating that these medications can influence immune function

For peptides, bioavailability varies dramatically depending on the delivery route

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However, these medications are not recommended for individuals who have had medullary thyroid cancer, as they want to affect several receptors together to get better treatment results