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The LASSS-stimulated mechanism is un-related to prevention of HGF nitration because all of the findings (shown in Figure 1e right panel, bars 810 and Figure 2a) were obtained under nitration-free conditions (omitting peroxynitrite treatment)
Regular follow-up every 412 weeks during initiation and dose titration, then every 36 months once stable, ensures appropriate safety surveillance for this inadequately studied combination
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