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These results clearly indicate that the observed induction of c-Ret phosphorylation by hHGF and aML5-PEG3 relies on Met phosphorylation, although we are not certain which factor(s) present in FBS plays a role in this transactivation event

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The exact molecular mechanisms leading to WL and glycaemia improvements with tirzepatide are still under investigation, mainly because the role of GIP receptor activation with tirzepatide is unclear

doi: 10.1016/j.polymer.2007.11.019 105

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