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Where positive effects have been observed, the magnitude of weight loss is typically smallgenerally in the range of 0.5-2 kgwhich may not be clinically meaningful for most individuals seeking weight management

Alkabbani W, Suissa K, Gu KD, Cromer SJ, Paik JM, Bykov K, et al

Functional studies further implicate occludin in maintaining epithelial architecture

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