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Seek immediate medical attention if you experience severe bleeding with faintness, confusion, or rapid heartbeat

In addition to their peripheral actions, GLP-1Rs are also expressed throughout the central nervous system, particularly within hypothalamic nuclei, septal regions, the brainstem and at lower levels in various cortical structures (Pyke et al., 2014

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Run retatrutide alone for the first 8 weeks, then add cagrilintide at the lowest dose (0.25 mg)

Rotate injection sites each weekalternating between your abdomen, thigh, and upper armto prevent lipohypertrophy (thickened skin from repeated injections in the same spot)