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Ozempic is FDA-approved for type 2 diabetes, and weight loss can happen as a side effect
GLP-1 receptor agonists exert their therapeutic effects through several mechanisms : they stimulate insulin secretion from pancreatic beta cells in a glucose-dependent manner, suppress glucagon release (which reduces hepatic glucose production), slow gastric emptying, and act on appetite centres in the hypothalamus to promote satiety and reduce food intake
Although GLP-1s are generally safe for the liver, its important to check, especially before compounded meds Kidney function: to watch for stress on the kidneys, which can be exacerbated by GLP-1-induced dehydration and nausea, especially in older adults or those with preexisting conditions [1] Thyroid markers : to screen for an under-functioning thyroid gland, which can mimic or worsen weight gain
Diabetes 60, 25982607
doi: 10.1056/NEJMoa1612917 252 MarsoSPDanielsGHBrown-FrandsenKKristensenPMannJFNauckMAet al
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