Class NNMT Inhibitor (Nicotinamide N-methyltransferase) Molecular Weight 193.2 Da (small molecule) Half-life Under investigation Purity 98% (HPLC) Form Powder Storage 20C, dry, protected from moisture Reconstitution DMSO or sterile water (partial solubility) Mechanism of action 5-Amino-1-methylquinolinium (5-Amino-1MQ) is a competitive inhibitor of NNMT an enzyme overexpressed in adipose tissue in obesity that converts nicotinamide to 1-methylnicotinamide while consuming SAM (S-adenosyl methionine)
Weight loss and metabolism Some studies suggest that higher vitamin B12 levels may protect against obesity or being overweight
In a natural sense, B12 can only be obtained from a diet that includes meat, eggs, and poultry
Metabolic Health & Insulin Sensitivity Modulation of NNMT activity has been associated with improved glucose handling and insulin sensitivity, suggesting potential benefits in metabolic syndrome and related conditions
GHK-Cu Has Broader Tissue Research GHK-Cu has been studied across a wider range of skin, wound-healing, tissue-remodeling, and inflammatory settings