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GLP-1 medicines are associated with a higher risk of gallstones and gallbladder problems, particularly at higher doses or with longer use

APOE genotype confers context-dependent neurovascular vulnerability in immune-vascularized human forebrain organoids

These drugs directly activate GLP-1 receptors, producing sustained appetite suppression, slower digestion to keep someone feeling full longer, and regulation of blood sugar

In preclinical studies, GLP-1 RAs reduced cytokine levels in various tissues, such as adipose and vascular tissues, which significantly contribute to inflammation associated with aging

CD8 + T cells regulate tumour ferroptosis during cancer immunotherapy