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ICV IgG1-treated mice maintained stable body weight, while all doses of ICV mGIPR-Ab/P3 led to substantial weight loss (Extended Data Fig

Clinical concern regarding skeletal muscle changes during GLP-1RA therapy remains debated [40], and preclinical studies have reported context-dependent protection against muscle wasting in selected settings [42, 43]

We usually recommend hormone replacement therapy for Addison's disease to address the insufficient production of cortisol and aldosterone

Typical dosages range from 100-200mg daily, preferably taken with a meal containing some fat to enhance absorption

Legumes and beans Beans, lentils, chickpeas, and other legumes are excellent sources of plant protein and fiber