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3-5 In monotherapy, no other oral treatment class has significantly shown higher efficacy in lowering HbA1c

doi:10.1111/j.1600-079X.2007.00524.x May-Panloup P, Boucret L, Chao de la Barca JM, et al

However, for advanced experimental models, it can be combined with NAD+ (for mitochondrial redox optimization) or SS-31 (for enhanced mitochondrial membrane protection)

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Aquellos con historia de pancreatitis requieren monitoreo cuidadoso