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A pivotal RCT in 116 cannabis-dependent adolescents found that NAC (1,200 mg twice daily) more than doubled the odds of a negative urine cannabinoid test compared to placebo (OR 2.4, 95% CI 1.1-5.2) (Gray et al., Am J Psychiatry, 2012) [76]
Statistical analysis Statistical analyses were performed using GraphPad Prism 6.0 package programme (GraphPad Software)
References: [1] Cell Mol Life Sci
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Sikiric et al., 1999c
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