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The severity of histopathological lesions was assessed and graded from five microscopic fields per rat using the classification system by Dommels et al
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elegans studies that mitochondrial-produced ROS can modulate neuropeptide release: in cholinergic motor neurons, neuropeptide-like protein (NLP-21) secretion was inhibited in two-different mutant types, both mutants causing enhanced mitochondrial ROS production via different mechanisms (Zhao et al
In an earlier study hesperidin has been reported to elevate SOD activity in iron overloaded rat liver [77]
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