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1), the study population was divided as follows: the GLP-1RA cohort consisted of patients prescribed initial GLP-1RAs between April 2013 and April 2019 who were never prescribed SGLT2 inhibitors before the initial GLP-1RAs prescription, and the SGLT2 cohort consisted of patients prescribed initial SGLT2 inhibitors between April 2013 and April 2019 who were never prescribed GLP-1RAs before the initial SGLT2 prescription
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This may help raise the anaerobic threshold, potentially delaying the onset of the lactic acid buildup that triggers a PEM crash after minor exertion
