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Acne occurs when hair follicles are clogged with oil, dead skin cells, and sometimes bacteria

Tumors in this subtype are usually resistant to endocrine therapy alone and only benefit when given additional treatments like chemotherapy or targeted therapy (97)

Prognostic significance of HER3 in patients with malignant solid tumors

However, the intranasal route of drug delivery still has some unresolved issues, such as the need to overcome cilia and mucosal clearance in the vestibular region, as well as enzymatic degradation after the introduction of nanotherapeutic formulations into the nasal cavity[166]

A., Ramos, M