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At the highest doses studied, tirzepatide users achieved approximately 22% weight loss versus 16% for semaglutide over 68 weeks

Notably, T memory cells, unlike T effector cells, do not uptake extracellular palmitate (126), delineating a stringent association between T cell subtype and preferences for fatty acid substrates

Some researchers have pointed out that the common digestive adverse reactions of the drug (diarrhea, vomiting, loss of appetite) may be contributing to their supposed weight loss success and are not ideal ways to support metabolic health at its foundation