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TNF- represses -Klotho expression and impairs FGF21 action in adipose cells: involvement of JNK1 in the FGF21 pathway

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work, Ipamorelin released GH with potency comparable to the older peptide GHRP-6 but, unlike GHRP-6 and GHRP-2, did not meaningfully elevate adrenocorticotropic hormone (ACTH), cortisol, or prolactin even at doses well above the GH-releasing threshold