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Klf4 overexpression activates epithelial cytokines and inflammation-mediated esophageal squamous cell cancer in mice
Always follow the dosing and safety instructions carefully when administering peptide therapy to ensure optimal results and minimize the risk of complications
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In vivo experiments further demonstrated that Irisin-loaded bone marrow mesenchymal stem cell-derived exosomes significantly inhibited activation of the YAP/EGR1/ACSL4 signaling pathway in the brains of middle cerebral artery occlusion (MCAO) mice, suppressed ferroptosis and lipid peroxidation, thereby mitigating ischemic brain injury ( In vitro experiments further confirmed that FGF21 protected HT22 cells from OGD/R-induced oxidative stress and ferroptosis, thereby attenuating neuronal injury (Zhao et al., 2025c)
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