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Do not double the dose to catch up

The practical takeaway: AOD-9604 has a clean safety profile in trials but a failed Phase 2b efficacy endpoint

Vegetarians and Vegans: Since vitamin B12 is primarily found in animal-based foods, individuals who follow vegetarian or vegan diets may not get adequate levels through food alone

124,147 Second-line antidepressants include tricyclic antidepressants (TCAs) (ie, amitriptyline [Elavil], clomipramine [Anafranil], and doxepin [Silenor]) and MAOIs (ie, tranylcypromine [Parnate] and phenelzine [Nardil])

As scientists continue to unlock the molecular mysteries of aging, 5-Amino-1MQ stands out as a research target that requires more human safety and efficacy data in the quest for a healthier, longer life